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Microclots can also be drawn into hematology analyzers and plug the tubing causing machine malfunction. Pyknotic leukocytes resemble and can be misinterpreted as nucleated red blood cells. Rough handling Shaking of blood tubes forcing through needles vigorous expulsion into can cause shearing red cells hemolysis platelet clumping. See also summary of some these artifacts [...]

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Dilution with fluids Collection of blood for hematologic testing through an indwelling catheter is not optimal but may be necessary critically ill patients that are being frequently sampled monitoring changes. display block n t if return LowerCase dexOf chromn chrdef mozsbr mozlbr moztsb sj evt nd onP var function ue . c function use strict var k G. Pg [...]

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The following anticoagulants can be used for hematologic testing however EDTA purple top is preferred . Binding of EDTAdependent antibodies to platelets and red blood cells can be overcome by collecting into citrate anticoagulant however routine collection is not recommended for reasons indicated below. Pyknotic leukocytes resemble and can be misinterpreted as nucleated red blood cells. part citrate to parts blood therefore all counts will be lower by least compared collected into EDTA [...]

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Elsevier Inc. A comprehensive list of all the tests offered by Clinical Pathology Laboratory Animal Health Diagnostic Center. V i G. Click here for information linking to our website using content images [...]

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Difficult venipuncture particularly through small gauge needle can result in shearing of red blood cells artifactual hemolysis which affects counts and mimics true intravascular . If only a small sample of blood is obtained microtainer tube containing EDTA anticoagulant preferred but sure to thoroughly mix the by gentle inversion several times. The following anticoagulants can be used for hematologic testing however EDTA purple top is preferred . Binding of EDTAdependent antibodies to platelets and red blood cells can be overcome by collecting into citrate anticoagulant however routine collection is not recommended for reasons indicated below [...]

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This a common artifact that we see in hematologic samples. Artifacts of specimen handling preparation can significantly impair examination blood cells but are easily avoided. The leukocyte nucleus has undergone pyknosis and karyorrhexis making certain identification impossible [...]

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The blood in tube should kept cold however slides stored and shipped at room temperature. StumbleUpon this PageSample collection and handling resourcesSite Directoryopen all close Advanced Search eClinpath About Us Terms of Service Privacy Policy Contact Suffusion theme by Sayontan Sinha Top Thank you Your feedback has been received. Ideally the catheter should be flushed with sterile saline to remove any contaminating intravenous fluids and first mL of blood discarded avoid dilutional effects [...]

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IG d typeof . Large platelet clumps are excluded from the count altogether. lab closed or when sending sample to reference smears should be made and sent along with the EDTA tube. Ideally the catheter should be flushed with sterile saline to remove any contaminating intravenous fluids and first mL of blood discarded avoid dilutional effects [...]

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Part citrate to parts blood therefore all counts will be lower by least compared collected into EDTA. Authors Blog Board Review Comment Contact Us Newsletters Statistics Testimonials Advertisement Read our about illegitimate journals and conferences click here Jobs Fellowships Webinars Books CME Case of Week Payment Industry Home Prostate gland seminal vesicles Grading Gleason Prostatic carcinoma Kenneth [...]

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The blood is diluted by citrate anticoagulant if appropriate volume ratio of to maintained . Shown at right is smear in which large obvious aggregates of stain precipitate are overlying the red cells. mL with placement into standard EDTA tube will cause shrinkage of red blood cells because is hypertonic [...]

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White blood cells Swellling and smoothing of the nuclear chromatin mimicking band neutrophil formation pyknosis karyhorrhexis nuclei smudging prominence hle bodies toxic change. Eventually cells will break down altogether rendering specimen useless for analysis. B Saunders Company [...]